New hope for kids with leukemia: drug combo aims to wipe out hidden cancer cells
NCT ID NCT05955261
First seen Dec 12, 2025 · Last updated Apr 30, 2026 · Updated 16 times
Summary
This study tests whether adding venetoclax to standard chemotherapy is safe and effective for children and young adults (up to age 22) with newly diagnosed acute myeloid leukemia (AML). The main goal is to see if the combination can clear even tiny amounts of cancer cells (called minimal residual disease) after the first round of treatment. About 70 participants will receive the drug combo, and researchers will track remission rates and survival over three years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital
Chicago, Illinois, 60611, United States
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Children's Hospital of Orange County
Orange, California, 92868, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20020, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Cook Children's Medical Center
Fort Worth, Texas, 76104, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Novant Health Presbyterian Medical Center
Charlotte, North Carolina, 28204, United States
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Rady Children's Hospital-San Diego
San Diego, California, 92123, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Valley Children's Hospital
Madera, California, 93636, United States
Conditions
Explore the condition pages connected to this study.