Promising combo targets tough blood cancers in early trial

NCT ID NCT04655755

First seen Oct 31, 2025 · Last updated May 02, 2026 · Updated 26 times

Summary

This study tests two drugs, venetoclax and ASTX727, in people with high-risk myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) who have not had treatment before. The goal is to find the best dose and see how well the combination controls the cancer. About 52 participants will be enrolled at MD Anderson Cancer Center.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.