Can an experimental pill help teenagers with vitiligo?
NCT ID NCT07828639
First seen Sep 18, 2026 · Last updated Sep 18, 2026
Summary
Researchers are testing an experimental oral drug called VC005 in teenagers aged 12 to 17 who have non-segmental vitiligo, a condition where patches of skin lose their color. The study measures how the drug moves through the body and checks for safety over up to 24 weeks of treatment. About 10 participants will take VC005 tablets, and researchers will also look for early signs of whether the drug helps repigment the skin.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- VC005 tablets, an experimental oral drug
- What this could lead to
- If VC005 proves safe and shows signs of helping, it could point toward an oral treatment option for teenagers with vitiligo, a condition with few therapies approved for this age group.
- What could go wrong
- This is a very small, early-stage study of only 10 teens with no control group, so it cannot prove the drug works. Many experimental drugs fail at this stage, and unknown side effects may emerge.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The subject fully understands this study and is able to comply with the relevant trial procedures. The subject and their legal guardian voluntarily sign the informed consent form (ICF). * Age 12 to 18 years inclusive (including 12 years old, excluding 18 years old) at the time of signing the ICF, both genders, with body weight ≥ 30 kg. * Subjects with a clinical diagnosis of non-segmental vitiligo Exclusion Criteria: * Pregnant or breastfeeding women, or subjects planning to become pregnant or breastfeed during the study period. * Trial participants with complete depigmentation of hair within the vitiligo area. * Trial participants clinically diagnosed with segmental vitiligo, mucosal non-segmental vitiligo, or other cutaneous depigmentation disorders.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Peking University People's Hospital
Beijing, Beijing Municipality, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New pill aims to bring back color to vitiligo skin
- New pill could help restore skin color in vitiligo patients
- Can a pill keep vitiligo at bay? new study aims to find out
- New hope for vitiligo: experimental drug aims to restore skin color
- New hope for vitiligo: experimental drug aims to bring back skin color
- Can a weekend steroid pill stop vitiligo spreading in kids?