Cure My Disease

Don't miss your cure!

 Log in / Sign up

New study aims to unlock secrets of graft infections using advanced blood tests

NCT ID NCT07696884

Knowledge-focused Sponsor: Aarhus University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study observes patients with suspected or diagnosed infections in central vascular grafts (like aortic grafts) to better understand how the body's immune system responds. Researchers will collect blood samples and clinical data over time, comparing infected patients to those receiving elective graft surgery and healthy blood donors. The goal is to improve diagnosis by testing new methods, including microbial cell-free DNA sequencing, which may detect infections more accurately than standard blood cultures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better and faster diagnosis of vascular graft infections, potentially improving treatment outcomes.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and findings may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Sep 2033

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study participants will be selected from clinical populations in the Central Denmark Region. Patients with suspected or diagnosed central vascular graft or endograft infection will be identified through infectious diseases and vascular/cardiothoracic surgical clinical care pathways, electronic medical records, and local departmental databases. Elective vascular graft/endograft control participants will be identified through the preoperative surgical pathway. Healthy blood donor controls will be selected from the Aarhus University Hospital Blood Bank during routine blood donation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Able and willing to provide informed consent. * For the vascular graft or endograft infection group: suspected or diagnosed vascular graft or endograft infection in a central vascular prosthesis as determined by the treating clinicians. * For the elective vascular graft or endograft control group: planned central vascular graft or endograft implantation. * For the healthy blood donor control group: active blood donor registered at Aarhus University Hospital Blood Bank. * For the healthy blood donor control group: no current infection or other active disease. Exclusion Criteria: * For the elective vascular graft or endograft control group: surgery performed as an emergency procedure within 24 hours. * For the elective vascular graft or endograft control group: reoperation of a previously implanted vascular graft or endograft. * For the elective vascular graft or endograft control group: evidence suggestive of ongoing infection in the area of surgery. * Unable to provide informed consent.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Aortic graft infection are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

prosthesis-related infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aortic graft infection Vascular endograft infection Vascular graft infection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus, 8200, Denmark