Could a Stop-Smoking drug ease IBS pain?
NCT ID NCT06854406
First seen Jan 07, 2026 · Last updated May 13, 2026 · Updated 18 times
Summary
This small pilot study tested whether varenicline, a drug typically used to help people quit smoking, could change how the rectum senses pressure in people with irritable bowel syndrome (IBS) and chronic belly pain. Eight adults with IBS (but not constipation type) took part. The goal was to see if the drug affects rectal sensation and pain thresholds, with safety also tracked.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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