Can a simple powder and wash stop joint infections? new study investigates

NCT ID NCT04075526

First seen Jan 09, 2026 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tested whether using vancomycin powder and a diluted iodine wash during joint replacement surgery could prevent serious infections in high-risk patients. Over 2,100 adults with conditions like osteoarthritis who were at higher risk due to factors like smoking or obesity took part. The goal was to see if these extra steps during surgery reduce the chance of infection around the new joint.

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Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Centura Health

    Denver, Colorado, 80210, United States

  • Cleveland Clinic Florida

    Weston, Florida, 33331, United States

  • Cleveland Clinic Ohio

    Cleveland, Ohio, 44195, United States

  • Columbia

    New York, New York, 10036, United States

  • Eisenhower Health

    Rancho Mirage, California, 92270, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • New England Baptist Hospital

    Boston, Massachusetts, 02120, United States

  • New York University Dept of Orthopedic Surgery

    New York, New York, 10003, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • St. Francis Hospital

    Roslyn, New York, 11576, United States

  • The Orthopedic Institute of New Jersey

    Sparta, New Jersey, 07871, United States

Conditions

Explore the condition pages connected to this study.