Obesity and antibiotics: study seeks safer dosing

NCT ID NCT06601257

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how to give the antibiotic vancomycin to obese adults. Researchers compared dosing based on weight versus kidney function to see which gives better drug levels. 35 healthy obese volunteers received a single dose and provided blood and urine samples. The goal is to improve safety and effectiveness of vancomycin in this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
vancomycin
What this could lead to
If successful, this could lead to better, safer dosing guidelines for vancomycin in people with obesity.
What could go wrong
This is a small, early-phase study with only 35 participants, so results may not apply to everyone. It focuses on drug levels, not direct treatment outcomes.

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Conditions

The condition(s) this trial relates to.

Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Michigan Clinical Research Unit

    Ann Arbor, Michigan, 48108, United States

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