New hope for duchenne: safer steroid alternative shows promise in boys

NCT ID NCT05185622

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tested a drug called vamorolone in 54 boys with Duchenne muscular dystrophy (DMD), a muscle-weakening disease. The goal was to see if the drug is safe and can help control the disease with fewer side effects than standard steroids. Boys aged 2 to under 4 and 7 to under 18 took the drug for 12 weeks, and researchers monitored their health and muscle function.

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Contacts and locations

Locations

  • Alberta's Children Hospital

    Calgary, Alberta, AB T3B 6A8, Canada

  • British Columbia Children's Hospital

    Vancouver, British Columbia, V6H 3N1, Canada

  • Children's Hospital of Eastern Ontario

    Ottawa, Ontario, K1H 8L1, Canada

  • Montreal Childrens Hospital

    Montreal, H4A 3J1, Canada

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

Conditions

Explore the condition pages connected to this study.