Could a common drug help heal traumatic brain injuries?
NCT ID NCT07166393
First seen Sep 30, 2025 · Last updated Apr 30, 2026 · Updated 27 times
Summary
This study tests whether a single dose of valproic acid, a drug already used for other conditions, can improve recovery in people with moderate to severe traumatic brain injury. About 432 adults aged 18-65 will receive either standard care plus a placebo or standard care plus one dose of valproic acid at a low or high dose. The goal is to see if the drug leads to better long-term outcomes and less brain damage.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of Arizona
Tucson, Arizona, 85719-4824, United States
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University of California, Davis
Sacramento, California, 95817, United States
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University of Southern California
Los Angeles, California, 90089-0701, United States
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University of Texas Southwestern
Dallas, Texas, 75390, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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