New hope for schizophrenia: valbenazine shows promise in phase 3 trial

NCT ID NCT05110157

Completed Symptom relief Sponsor: Neurocrine Biosciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding valbenazine to standard antipsychotic medication helps reduce schizophrenia symptoms in adults who did not respond well to treatment alone. Over 400 participants took either valbenazine or a placebo for 10 weeks. Researchers measured changes in symptom severity, overall illness, and daily functioning.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA

Contacts and locations

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Locations

Neurocrine Clinical Site

Anaheim, California, 92805, United States
Neurocrine Clinical Site

Bellflower, California, 90706, United States
Neurocrine Clinical Site

Culver City, California, 90230, United States
Neurocrine Clinical Site

Garden Grove, California, 92845, United States
Neurocrine Clinical Site

Lemon Grove, California, 91945, United States
Neurocrine Clinical Site

Long Beach, California, 90807, United States
Neurocrine Clinical Site

Oceanside, California, 92056, United States
Neurocrine Clinical Site

Pico Rivera, California, 90660, United States
Neurocrine Clinical Site

Riverside, California, 92506, United States
Neurocrine Clinical Site

San Diego, California, 92102, United States
Neurocrine Clinical Site

San Diego, California, 92103, United States
Neurocrine Clinical Site

San Jose, California, 95124, United States
Neurocrine Clinical Site

Santa Ana, California, 92705, United States
Neurocrine Clinical Site

Stanford, California, 94305, United States
Neurocrine Clinical Site

Torrance, California, 90502, United States
Neurocrine Clinical Site

Aventura, Florida, 33180, United States
Neurocrine Clinical Site

Coral Gables, Florida, 33134, United States
Neurocrine Clinical Site

Daytona Beach, Florida, 32114, United States
Neurocrine Clinical Site

Hialeah, Florida, 33012, United States
Neurocrine Clinical Site

Hialeah, Florida, 33013, United States
Neurocrine Clinical Site

Hialeah, Florida, 33016, United States
Neurocrine Clinical Site

Miami, Florida, 33133, United States
Neurocrine Clinical Site

Miami, Florida, 33137, United States
Neurocrine Clinical Site

Miami, Florida, 33144, United States
Neurocrine Clinical Site

Miami Lakes, Florida, 33016, United States
Neurocrine Clinical Site

Okeechobee, Florida, 34972, United States
Neurocrine Clinical Site

Tampa, Florida, 33629, United States
Neurocrine Clinical Site

West Palm Beach, Florida, 33407, United States
Neurocrine Clinical Site

Atlanta, Georgia, 30328, United States
Neurocrine Clinical Site

Evanston, Illinois, 60208, United States
Neurocrine Clinical Site

Springfield, Illinois, 62702, United States
Neurocrine Clinical Site

Grand Rapids, Michigan, 49503, United States
Neurocrine Clinical Site

St Louis, Missouri, 63125, United States
Neurocrine Clinical Site

St Louis, Missouri, 63128, United States
Neurocrine Clinical Site

Lincoln, Nebraska, 68526, United States
Neurocrine Clinical Site

Las Vegas, Nevada, 89102, United States
Neurocrine Clinical Site

Cedarhurst, New York, 11516, United States
Neurocrine Clinical Site

New York, New York, 10032, United States
Neurocrine Clinical Site

New York, New York, 10035, United States
Neurocrine Clinical Site

Charlotte, North Carolina, 28211, United States
Neurocrine Clinical Site

Dayton, Ohio, 45417, United States
Neurocrine Clinical Site

Oklahoma City, Oklahoma, 73112, United States
Neurocrine Clinical Site

Austin, Texas, 78754, United States
Neurocrine Clinical Site

Dallas, Texas, 75390, United States
Neurocrine Clinical Site

DeSoto, Texas, 75115, United States
Neurocrine Clinical Site

Houston, Texas, 77081, United States
Neurocrine Clinical Site

Houston, Texas, 77090, United States
Neurocrine Clinical Site

Buenos Aires, 1133, Argentina
Neurocrine Clinical Site

Córdoba, 5004, Argentina
Neurocrine Clinical Site

Kardzhali, 6600, Bulgaria
Neurocrine Clinical Site

Lovech, 5500, Bulgaria
Neurocrine Clinical Site

Plovdiv, 4002, Bulgaria
Neurocrine Clinical Site

Plovdiv, 4004, Bulgaria
Neurocrine Clinical Site

Rousse, 7003, Bulgaria
Neurocrine Clinical Site

Sofia, 1113, Bulgaria
Neurocrine Clinical Site

Sofia, 1408, Bulgaria
Neurocrine Clinical Site

Sofia, 1510, Bulgaria
Neurocrine Clinical Site

Sofia, 1680, Bulgaria
Neurocrine Clinical Site

Veliko Tarnovo, 5000, Bulgaria
Neurocrine Clinical Site

Vratsa, 3000, Bulgaria
Neurocrine Clinical Site

Belgrade, 11108, Serbia
Neurocrine Clinical Site

Gornja Toponica, 18202, Serbia
Neurocrine Clinical Site

Niš, 18000, Serbia
Neurocrine Clinical Site

Niš, 34000, Serbia
Neurocrine Clinical Site

Novi Kneževac, 23330, Serbia
Neurocrine Clinical Site

Vojvodina, 26300, Serbia
Neurocrine Clinical Site

Vršac, 26300, Serbia
Neurocrine Clinical Site

Phoenix, Arizona, 85012, United States
Neurocrine Clinical Site

Rogers, Arkansas, 72758, United States
Neurocrine Clinical Site 1

Pleven, 5800, Bulgaria
Neurocrine Clinical Site 1

Plovdiv, 4000, Bulgaria
Neurocrine Clinical Site 1

Sofia, 1000, Bulgaria
Neurocrine Clinical Site 1

Belgrade, 11000, Serbia
Neurocrine Clinical Site 1

Kovin, 26220, Serbia
Neurocrine Clinical Site 1

Kragujevac, 34000, Serbia
Neurocrine Clinical Site 2

Pleven, 5800, Bulgaria
Neurocrine Clinical Site 2

Plovdiv, 4000, Bulgaria
Neurocrine Clinical Site 2

Sofia, 1000, Bulgaria
Neurocrine Clinical Site 2

Belgrade, 11000, Serbia
Neurocrine Clinical Site 2

Kovin, 26220, Serbia
Neurocrine Clinical Site 2

Kragujevac, 34000, Serbia
Neurocrine Clinical Site 3

Belgrade, 11000, Serbia
Neurocrine Clinical Site 3

Kragujevac, 34000, Serbia
Neurocrine Clinical Site 4

Belgrade, 11000, Serbia
Neurocrine Clinical Site 5

Belgrade, 11000, Serbia
Neurocrine Clinical Site 6

Belgrade, 11000, Serbia
Neurocrine Clinical Sites

Glen Oaks, New York, 11004, United States

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