Could a vaginal 'Microbiome Transplant' fix bacterial imbalance?
NCT ID NCT05850078
First seen Jan 08, 2026 · Last updated Jun 23, 2026 · Updated 21 times
Summary
This completed trial tested whether a vaginal microbiome transplant called FB101 can shift the balance of bacteria in healthy women who have an imbalance (dysbiosis). 97 pre-menopausal women received either FB101, a diluted version, or a placebo. The goal was to see if the treatment could increase the relative abundance of healthy Lactobacillus species.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atlantia Clinical Trials
Cork, Ireland
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FB101 (vaginal microbiome transplant)
What this could lead to
If it works, this could point toward a treatment for vaginal dysbiosis by restoring healthy bacteria without long-term medication.
What could go wrong
This is an early, small study in healthy volunteers, so results may not apply to people with symptoms. The intervention is still experimental and may not change the microbiome as hoped.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.