Could a vaginal 'Microbiome Transplant' fix bacterial imbalance?
NCT ID NCT05850078
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed trial tested whether a vaginal microbiome transplant called FB101 can shift the balance of bacteria in healthy women who have an imbalance (dysbiosis). 97 pre-menopausal women received either FB101, a diluted version, or a placebo. The goal was to see if the treatment could increase the relative abundance of healthy Lactobacillus species.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- FB101 (vaginal microbiome transplant)
- What this could lead to
- If it works, this could point toward a treatment for vaginal dysbiosis by restoring healthy bacteria without long-term medication.
- What could go wrong
- This is an early, small study in healthy volunteers, so results may not apply to people with symptoms. The intervention is still experimental and may not change the microbiome as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Atlantia Clinical Trials
Cork, Ireland
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