Could vaginal bacteria hold key to better sex life for breast cancer patients?

NCT ID NCT05946668

First seen Jun 06, 2026 · Last updated Jun 20, 2026 · Updated 3 times

Summary

This study examined the vaginal microbiome—the collection of bacteria and other microbes—in 35 women with breast cancer receiving hormone therapy. Researchers wanted to see if changes in these microbes relate to vaginal dryness and sexual health. Participants provided vaginal swabs and filled out questionnaires. The goal is to find a biomarker that could one day lead to better ways to manage sexual health side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify a biomarker to predict or improve vaginal and sexual health in breast cancer patients on hormone therapy.

What could go wrong

This is a small, completed observational study with only 35 participants. Results may not apply to all patients, and it does not test a treatment directly.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.