Nerve-Gut link in HIV: could stimulation reduce inflammation?

NCT ID NCT04353778

First seen Feb 20, 2026 · Last updated Jun 18, 2026 · Updated 15 times

Summary

This study looks at how a damaged vagus nerve may cause gut problems and inflammation in people with HIV. Researchers will test 207 adults with HIV to see if a drug called pyridostigmine or vagus nerve stimulation can help. The goal is to understand these pathways and find new ways to reduce inflammation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

HIV infectious disease vagus nerve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.