Could a pill replace needles for anemia in dialysis?

NCT ID NCT06520826

Ongoing Disease control Sponsor: USRC Kidney Research Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an oral drug called vadadustat (Vafseo) for treating anemia in people with end-stage kidney disease who are on hemodialysis. About 2,200 adults will be randomly assigned to take vadadustat three times a week or continue standard injectable treatments. The goal is to see if the oral drug is as safe and effective at managing anemia and reducing hospitalizations or death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vadadustat (Vafseo)
What this could lead to: If successful, this could offer a more convenient oral option for managing anemia in dialysis patients, potentially reducing hospitalizations.
What could go wrong: This is a large Phase 3 trial, but it's comparing to existing treatments, not testing a cure. Risks include side effects and the possibility that vadadustat is no better or worse than current standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anemia due to chronic disorder end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEMIA OF CHRONIC KIDNEY DISEASE

Contacts and locations

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Locations

Dallas Renal Group

Dallas, Texas, 75230, United States
Nephrology and Hypertension Specialists, PC

Dalton, Georgia, 30720, United States
US Renal Care - Gallup

Gallup, New Mexico, 87301, United States
US Renal Care - Live Oak

Live Oak, Texas, 78233, United States
USRC Kidney Research

Lone Tree, Colorado, 80124, United States

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