Own cells implanted in brain to fight Parkinson's

NCT ID NCT06778265

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests a new treatment called UX-DA001 for people with Parkinson's disease. The treatment uses the patient's own cells, which are turned into dopamine-producing cells and implanted into the brain during surgery. The main goal is to check safety, but researchers will also look for signs that motor function improves. Only 12 people aged 50-75 with advanced Parkinson's will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

UX-DA001 (human midbrain dopaminergic progenitor cells made from the patient's own cells)

What this could lead to

If it works, this could point toward a treatment that replaces lost dopamine cells and improves motor function in Parkinson's disease.

What could go wrong

This is a very early Phase 1 trial with only 12 people, focused on safety. It may not improve symptoms, and surgery carries risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200025, China