New ALS drug usnoflast enters key trial to slow deadly disease
NCT ID NCT07023835
First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times
Summary
This study tests whether the drug usnoflast can slow the progression of ALS, a severe nerve disease that causes muscle weakness and breathing problems. About 240 adults with ALS will receive either usnoflast or a placebo for 36 weeks. Researchers will measure changes in daily function and survival to see if the drug helps control the disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zydus 100
ACTIVE_NOT_RECRUITINGQuébec, Quebec, QC H4A 3T2, Canada
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Zydus 101
NOT_YET_RECRUITINGToronto, Ontario, ON M4N 3M5, Canada
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Zydus US001
RECRUITINGDallas, Texas, 75206, United States
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Zydus US002
RECRUITINGHouston, Texas, 77030, United States
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Zydus US003
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Zydus US004
RECRUITINGRichmond, Virginia, 23298, United States
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Zydus US005
RECRUITINGNew Britain, Connecticut, 06053, United States
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Zydus US006
RECRUITINGDetroit, Michigan, 48202, United States
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Zydus US007
NOT_YET_RECRUITINGAtlanta, Georgia, 30322, United States
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Zydus US008
NOT_YET_RECRUITINGOrange, California, 92868, United States
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Zydus US009
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15212, United States
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Zydus US010
RECRUITINGBoston, Massachusetts, 02114, United States
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Zydus US011
RECRUITINGSeattle, Washington, 98122, United States
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Zydus US012
RECRUITINGTampa, Florida, 80045, United States
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Zydus US013
NOT_YET_RECRUITINGSan Francisco, California, 94109, United States
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Zydus US014
RECRUITINGLincoln, Nebraska, 68510, United States
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Zydus US015
RECRUITINGLa Jolla, California, 92037, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a gentle brain ZAP help ALS patients breathe easier?