Can a gut drug prevent pneumonia in disabled kids?

NCT ID NCT05455359

First seen Jan 11, 2026 · Last updated May 05, 2026 · Updated 17 times

Summary

This study looks at whether problems with how the stomach and esophagus move can increase the risk of breathing food or liquid into the lungs (aspiration) in children with brain-related disabilities. The researchers are comparing two medicines—prucalopride and famotidine—over 10 weeks to see which one better reduces coughing and other aspiration symptoms. The study includes 120 children aged 5-21 who get most of their nutrition through a feeding tube and are at high risk for aspiration pneumonia.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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