Off-the-Shelf cell therapy takes on tough leukemia

NCT ID NCT07432100

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new type of CAR-T cell therapy for adults with acute myeloid leukemia (AML) that has come back or not responded to standard treatments. The therapy uses donor cells engineered to target a protein called CLL1 found on most AML cells, and is designed to be ready-to-use, avoiding the long wait of personalized CAR-T. The study will enroll 20 participants to check safety, how well the cells work, and how long any benefits last.

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Conditions

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