Scientists dig into why some people get severe valley fever

NCT ID NCT02190266

First seen Jun 24, 2026 · Last updated Jul 29, 2026 · Updated 8 times

Summary

This study looks at people with severe or hard-to-treat Valley Fever, a lung infection caused by a fungus found in the southwestern U.S. Researchers want to understand why some people get seriously ill by studying their immune systems and genetics. Up to 400 participants will give blood, urine, and sputum samples and have yearly check-ups. The goal is to learn more about the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new ways to treat or prevent severe Valley Fever by identifying immune system weaknesses.
What could go wrong
This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results could take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.