Your unique 'Sync Signature' could be key to beating depression
NCT ID NCT06749392
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how the natural rhythm of connection between a therapist and patient—called synchrony—might help treat depression. Researchers will track 78 adults with major depressive disorder over 16 weeks of supportive-expressive therapy. The goal is to see if each person has a unique synchrony pattern and whether adjusting therapy to match that pattern leads to better mood and fewer symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
supportive-expressive psychotherapy
What this could lead to
If successful, this could lead to more personalized psychotherapy approaches that tailor the therapist-patient connection to each individual's needs, potentially improving depression treatment outcomes.
What could go wrong
This is an early-stage observational study with only 78 participants, so results may not apply to everyone. The concept of 'synchrony signatures' is new and unproven, and the study may not find clear links to symptom improvement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Haifa
RECRUITINGHaifa, 3498838, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••