1,000 volunteers needed to unlock secrets of sickle cell trait

NCT ID NCT06071377

Recruiting now Knowledge-focused Sponsor: National Alliance for Sickle Cell Centers Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 1,000 adults who have sickle cell trait (SCT) to better understand how it affects their health. Researchers will collect blood and urine samples to measure hemoglobin levels, blood cell properties, and signs of kidney or clotting problems. The goal is to learn why some people with SCT develop complications while others do not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal which people with sickle cell trait are at higher risk for health problems like kidney disease, helping doctors monitor them better.
What could go wrong: This is an observational study, not a treatment trial. It will not test any drug or therapy, so it cannot directly improve health. Results may take years and might not lead to clear changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sickle Cell Trait

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SICKLE CELL TRAIT

Contacts and locations

Locations

Duke University
RECRUITING

Durham, North Carolina, 27710, United States
East Carolina University
RECRUITING

Greenville, North Carolina, 27834, United States
Functional Fluidics
RECRUITING

Detroit, Michigan, 48202, United States
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Loma Linda University Health Care
RECRUITING

Loma Linda, California, 92354, United States
Nationwide Children's Hospital
RECRUITING

Columbus, Ohio, 43205, United States
Nemours Children's Hospital
RECRUITING

Wilmington, Delaware, 19803, United States
UT Health Houston
RECRUITING

Houston, Texas, 77030, United States
University of Alabama
RECRUITING

Birmingham, Alabama, 35294, United States
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27599, United States

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