Small study dives into how new drug works for ulcerative colitis

NCT ID NCT03100864

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 26 times

Summary

This study looked at how a new medicine, BI 655130, affects the body in 8 adults with moderate to severe ulcerative colitis. The main goal was to understand the drug's mechanism by measuring changes in gene activity in the gut lining. Researchers also checked for safety and signs of improvement, but this was an early exploratory trial, not a test for a cure.

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Contacts and locations

Locations

  • Addenbrooke's Hospital

    Cambridge, CB2 0QQ, United Kingdom

  • Asklepios Kliniken Westklinikum Hamburg

    Hamburg, 22559, Germany

  • UZ Leuven

    Leuven, 3000, Belgium

  • Universitätsklinikum Schleswig-Holstein, Campus Kiel

    Kiel, 24105, Germany

Conditions

Explore the condition pages connected to this study.