Cord blood stem cells take on deadly transplant complication
NCT ID NCT03847844
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether stem cells from donated umbilical cords (Cyto-MSC) could help treat acute graft-versus-host disease (GVHD), a serious complication after bone marrow transplants. Twenty-six patients with moderate to severe GVHD received the stem cells plus standard steroids. The goal was to see if this combination could improve response rates and survival. The trial was completed, but results are not yet widely reported.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
umbilical cord mesenchymal stem cells (Cyto-MSC)
What this could lead to
If it works, this could provide a new front-line treatment option for acute graft-versus-host disease, potentially improving survival and reducing complications.
What could go wrong
This is an early-phase trial with only 26 participants, so results may not apply to all patients. Stem cell therapies can carry risks like infection or immune reactions.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital Ampang
Ampang, Selangor, 68000, Malaysia