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Ultrasound may make bone marrow biopsies less painful and more accurate

NCT ID NCT05258357

Knowledge-focused Sponsor: Medical College of Wisconsin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study tests whether using ultrasound to guide a bone marrow biopsy is better than the usual method of feeling for landmarks on the body. The researchers will compare pain, sample quality, and procedure time in 100 hospitalized adults. If ultrasound helps, it could lead to more comfortable and successful biopsies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound-assisted bone marrow biopsy procedure
What this could lead to
If ultrasound guidance proves better, it could become the standard method for bone marrow biopsies, making them less painful and more reliable.
What could go wrong
This is a small, early-stage study (100 participants) comparing two techniques, so results may not apply to all patients or settings. The benefits of ultrasound are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

May 2022

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Inpatient at Froedtert \& MCW Froedtert Hospital ≥18 years old. 2. Inpatient at Froedtert \& MCW Froedtert Hospital requiring a bone marrow biopsy performed by the Medicine Bedside Procedure Team. 3. Bone marrow biopsy is being performed for the explicit purpose of hematology/oncology assessment. 4. Personally or via power of attorney (POA) in-person consent to the bone marrow biopsy procedure. 5. Provide written informed consent to be on the study. 6. English speaking Exclusion Criteria: 1. Inpatient at Froedtert \& MCW Froedtert Hospital \<18 years old. 2. Inpatient having no indication for bone marrow biopsy. 3. BMI ≥ 40. 4. Inpatient that does not consent to the procedure themselves or have a POA that does not consent to the procedure.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone marrow biopsy procedure

Contacts and locations

Locations

  • Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States