New nerve block could slash opioid use after spine surgery
NCT ID NCT07334288
First seen Jan 12, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tests whether an ultrasound-guided nerve block, given before lumbar spine surgery, can reduce the need for strong painkillers (opioids) afterward. Fifty adults scheduled for back surgery will be randomly assigned to receive either the nerve block plus standard pain care or standard care alone. Researchers will measure total opioid use in the first 24 hours, pain levels, and recovery outcomes.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clínica Universidad de los Andes, Chile
RECRUITINGSantiago, Santiago Metropolitan, 171571, Chile
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bupivacaine and Epinephrine (injected as a nerve block)
What this could lead to
If it works, this could offer a better way to manage pain after back surgery, reducing the need for strong opioids.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply to everyone. The nerve block itself carries small risks like bleeding or infection.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.