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Fibroid treatment showdown: which procedure stands the test of time?

NCT ID NCT02100904

Ongoing Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This nationwide registry follows 578 women with uterine fibroids who choose either radiofrequency ablation (Acessa) or myomectomy. Researchers track symptom changes, quality of life, and need for repeat treatment over three years. The goal is to understand which procedure provides better long-term relief and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiofrequency ablation (Acessa) or myomectomy
What this could lead to
If successful, this study could provide clear evidence on which fibroid treatment offers better long-term symptom relief and fewer repeat procedures.
What could go wrong
This is an observational registry, not a controlled trial, so results may be influenced by patient choice and other factors. It tracks outcomes but does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

leiomyoma uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UTERINE FIBROIDS

Contacts and locations

Locations

  • Acacia OBGYN

    San Antonio, Texas, 78217, United States

  • Dedicated to Women

    Dover, Delaware, 19904, United States

  • Duke University

    Durham, North Carolina, 27704, United States

  • Fibroid and Pelvic Wellness Center of Georgia

    Alpharetta, Georgia, 30005, United States

  • Gynecology Institute of Chicago

    Chicago, Illinois, 60605, United States

  • MacArthur Medical Center

    Irving, Texas, 75062, United States

  • Tassone Advanced Gynecology

    Austin, Texas, 78723, United States

  • UC Irvine Medical Center

    Irvine, California, 92868, United States

  • UT Southwestern

    Dallas, Texas, 75390, United States

  • University of California, San Diego

    San Diego, California, 92037, United States

  • University of California, San Francisco

    San Francisco, California, 94115, United States

  • Women's Healthcare Associates of IL, SC

    Homewood, Illinois, 60430, United States

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