Elbow nerve surgery showdown: which procedure works best?

NCT ID NCT04254185

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares two common surgeries for ulnar neuropathy at the elbow: simple decompression and subcutaneous anterior transposition. Researchers will enroll 378 adults with confirmed ulnar nerve issues to see which surgery better improves hand function and reduces pain. Participants will be followed for up to 24 months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Simple decompression (in-situ decompression) or subcutaneous anterior transposition (surgical techniques)
What this could lead to
If this trial succeeds, it could show which surgery is more effective for relieving ulnar nerve symptoms, helping doctors choose the best approach for patients.
What could go wrong
This is a comparative effectiveness trial, not a test of a new cure. Results may show only modest differences, and individual outcomes can vary. Risks include surgical complications like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Curtis National Hand Center

    RECRUITING

    Baltimore, Maryland, 21218, United States

  • Emory Healthcare

    RECRUITING

    Atlanta, Georgia, 30329, United States

  • Johns Hopkins University

    TERMINATED

    Baltimore, Maryland, 21093, United States

  • Michigan Medicine

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Norton Healthcare

    RECRUITING

    Louisville, Kentucky, 40241, United States

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

  • OrthoCarolina Research Institute, Inc.

    RECRUITING

    Charlotte, North Carolina, 28207, United States

  • University of Oklahoma

    RECRUITING

    Oklahoma City, Oklahoma, 73126, United States

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States