Experimental combo for stomach and bowel cancers shows early promise, but study halted
NCT ID NCT05221320
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times
Summary
This study tested two drugs, ulixertinib and hydroxychloroquine, together in 47 adults with advanced gastrointestinal cancers that have certain gene mutations (MAPK pathway). The goal was to see if the combination could shrink tumors or slow cancer growth. The trial was terminated early, so final results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Massey Cancer Center, Virginia Commonwealth University
Richmond, Virginia, 23298, United States
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Mount Sinai
New York, New York, 10029, United States
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Rogel Cancer Center, University of Michigan Health
Ann Arbor, Michigan, 48109, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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University of Arizona Cancer Center
Tucson, Arizona, 85719, United States
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University of California San Francisco
San Francisco, California, 94143, United States
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University of Kansas Cancer Center
Fairway, Kansas, 66205, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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