Scientists test if new drug can penetrate the Brain's defenses

NCT ID NCT05804227

Summary

This early-phase study aims to find out if the experimental drug ulixertinib can cross the blood-brain barrier and reach recurrent brain tumors called gliomas. It will enroll about 40 adults and teenagers (12+) whose tumors have a specific genetic change (MAPK-activated). The main goal is to measure how much of the drug gets into the tumor tissue during a short treatment window before planned surgery, or to see if it shows any anti-tumor activity in patients not having surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.