New drug shows promise for Hard-to-Treat bowel disease
NCT ID NCT06049017
Summary
This study tested whether an experimental drug called JNJ-77242113 could help adults with moderate-to-severe ulcerative colitis who hadn't responded well to standard treatments. Researchers compared the drug against a placebo in 252 participants over 12 weeks to see if it reduced symptoms and inflammation. The main goal was to determine if the treatment was both safe and effective at controlling this chronic bowel condition.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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ABP Research Services Corp.
Oakville, Ontario, L6L 5L7, Canada
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APHP - Hopital Bichat - Claude Bernard
Paris, 75018, France
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APHP - Hopital Henri Mondor
Créteil, 94000, France
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AZ Sint-Lucas
Ghent, 9000, Belgium
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Accurate Clinical Research, Inc.
Humble, Texas, 77346, United States
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Addenbrookes Hospital
Cambridge, CB2 0QQ, United Kingdom
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Amel Med LLC Research
Georgetown, Texas, 78628, United States
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Aoyama Naika Clinic
Kobe, 650-0015, Japan
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Asan Medical Center
Seoul, 05505, South Korea
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Atlanta Gastroenterology Associates
Atlanta, Georgia, 30342, United States
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Atrium Health
Charlotte, North Carolina, 28204, United States
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Azienda Ospedaliera San Camillo - Roma
Roma, 00152, Italy
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BR TRIALS Ensaios Clinicos e Consultoria Ltda
São Paulo, 01236030, Brazil
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Barrie GI Associates
Barrie, Ontario, L4M 7G1, Canada
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Barts Health NHS Trust
London, E11 1NR, United Kingdom
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Blacktown Hospital
Blacktown, 2148, Australia
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Bodyclinic Sp. z o.o. sp. k
Warsaw, 03 712, Poland
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CDC - Centro Digestivo de Curitiba
Curitiba, 80430-180, Brazil
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CHRU Besancon Hopital Jean Minjoz
Besançon, 25030, France
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CHRU de Lille Hopital Claude Huriez
Lille, 59037, France
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CHU Nimes Hopital Caremeau
Nîmes, 30900, France
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CHU Saint Etienne Hopital Nord
Saint-Priest-en-Jarez, 42270, France
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CHU Saint-Pierre
Brussels, 1000, Belgium
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CHU Toulouse - Hopital de Rangueil
Toulouse, 31400, France
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CHU de Nancy_ Hopital Brabois
Vandœuvre-lès-Nancy, 54500, France
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CHU de Nice Hopital de l Archet
Nice, 06202, France
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CIPREC
Buenos Aires, C1061AAS, Argentina
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Caprock Gastro Research
Lubbock, Texas, 79424, United States
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Care Access Research, Ogden
Ogden, Utah, 84403, United States
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Casa Sollievo Della Sofferenza IRCCS
San Giovanni Rotondo, 71013, Italy
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Centralny Szpital Kliniczny Mswia
Warsaw, 02 507, Poland
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Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman
Liège, 4000, Belgium
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Centre Hospitalier de l'Universite de Montreal
Montreal, Quebec, H2X 0C1, Canada
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Centrul Medical Valahia
Ploieşti, 100032, Romania
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Centrum Medyczne Lukamed Spolka z Ograniczona Odpowiedzialnoscia
Chojnice, 89-600, Poland
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Centrum Medyczne Medis ManerMed Sp Z O O
Bydgoszcz, 85 229, Poland
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Centrum Medyczne Medyk
Rzeszów, 35-326, Poland
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Centrum Medyczne Oporow
Wroclaw, 52 416, Poland
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Centrum Medyczne Plejady
Krakow, 30 363, Poland
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Cer Instituto Medico
Buenos Aires, B1878DVB, Argentina
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Charlotte Gastroenterology and Hepatology, PLLC
Charlotte, North Carolina, 28207, United States
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Chongqing General Hospital
Chongqing, 400014, China
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Clinexpert Kft
Gyöngyös, 3200, Hungary
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Clinique Ambroise Pare
Neuilly-sur-Seine, 92200, France
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Clinnova Research
Anaheim, California, 92805, United States
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Concord Repatriation General Hospital
Concord, 2139, Australia
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Cotton O'Neil Digestive Health Center
Topeka, Kansas, 66606, United States
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DHAT Research Institute
Garland, Texas, 75044, United States
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Debreceni Egyetem Gasztroenterologiai Klinika
Debrecen, 4032, Hungary
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DiGiovanna Institute for Medical Education & Research
North Massapequa, New York, 11758, United States
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Digenio - Centrul Medical de Gastroenterologie, Hepatologie si Endoscopie Digestiva
Cluj-Napoca, 400061, Romania
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Digestive Disease Specialists Inc
Oklahoma City, Oklahoma, 73112, United States
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EMC Instytut Medyczny SA
Wroclaw, 54 144, Poland
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Ege Universitesi Tip Fakultesi
Izmir, 35040, Turkey (Türkiye)
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Endoscopic Research Inc
Orlando, Florida, 32803-1853, United States
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Eugastro GmbH
Leipzig, 04103, Germany
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Fairfield General Hospital
Bury, Greater Manchester, United Kingdom
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Fondazione IRCCS Ca Granda Ospedale Policlinico Di Milano
Milan, 20122, Italy
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Fondazione Policlinico Universitario A Gemelli IRCCS
Roma, 00168, Italy
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GASTROMED Sp. z o.o.
Torun, 87 100, Poland
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GCP Clinical Research
Tampa, Florida, 33609, United States
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Gastroenterologie, s.r.o., Hradec Kralove
Hradec Kralova, 500 02, Czechia
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Gastroenterologische Gemeinschaftspraxis Minden
Minden, 32423, Germany
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Gastroenterology Associates P.A.
Greenville, South Carolina, 29607, United States
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Gastroenterology Associates of Tidewater
Chesapeake, Virginia, 23320, United States
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Gastroenterology and Internal Medicine Research Institute (GIRI)
Edmonton, Alberta, T5R 1W2, Canada
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Gastroenterology of Southern Indiana
New Albany, Indiana, 47150, United States
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Gazi University Medical Faculty
Ankara, 6500, Turkey (Türkiye)
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Gedyt - Consultorios Gastroenterologia
Buenos Aires, C1425, Argentina
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Ghent University Hospital
Ghent, 9000, Belgium
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Govind Ballabh Pant Hospital
New Delhi, 110002, India
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Guys St Thomas Hospital
London, SE1 7EH, United Kingdom
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Hamamatsu University Hospital
Hamamatsu, 431 3192, Japan
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Hepato-gastroenterologie HK, s.r.o.
Hradec Králové, 500 12, Czechia
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Hoag Memorial Hospital
Newport Beach, California, 92663, United States
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Hosp. Alvaro Cunqueiro
Vigo, 36312, Spain
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Hosp. Arquitecto Marcide
Ferrol, 15405, Spain
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Hosp. Clinico Univ. de Santiago
Santiago de Compostela, 15706, Spain
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Hosp. Clinico Univ. de Valencia
Valencia, 46010, Spain
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Hosp. Ntra. Sra. de Valme
Seville, 41014, Spain
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Hosp. Univ. Fundacion Alcorcon
Alcorcón, 28922, Spain
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Hosp. Univ. I Politecni La Fe
Valencia, 46026, Spain
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Hosp. Univ. La Paz
Madrid, 28046, Spain
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Hosp. Univ. Pta. de Hierro Majadahonda
Majadahonda, 28222, Spain
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Hosp. Virgen Macarena
Seville, 41009, Spain
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Hosp. de Cabuenes
Gijón, 33394, Spain
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Hospices Civils de Lyon CHU Lyon Sud
Pierre-Bénite, 69495, France
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Hospital Provincial del Centenario
Rosario, S2000KDS, Argentina
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Hospital Sultanah Aminah
Johor Bahru, 80100, Malaysia
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Hospital de Clinicas de Porto Alegre - Hospital de Clinicas
Porto Alegre, 90035 903, Brazil
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I.H.S. Health. LLC
Kissimmee, Florida, 34741, United States
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INTEGRAL Pesquisa e Ensino
Votuporanga, 15501-405, Brazil
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ISCARE a.s.
Prague, 19000, Czechia
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Inje University Haeundae Paik Hospital
Busan, 48108, South Korea
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Instituto D Or de Pesquisa e Ensino
São Paulo, 01401 002, Brazil
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Istituto Clinico Humanitas
Rozzano, 20089, Italy
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Japanese Red Cross Osaka Hospital
Osaka, 543 8555, Japan
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Kagoshima IBD Gastroenterology Clinic
Kagoshima, 892-0843, Japan
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Kangbuk Samsung Hospital
Seoul, 03181, South Korea
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Kings College Hospital
London, SE5 9RS, United Kingdom
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Kinshukai Infusion Clinic
Osaka, 530-0011, Japan
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Klinikum Augsburg
Augsburg, D-86158, Germany
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Krankenhaus Waldfriede Mitte
Berlin, 14163, Germany
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L2IP Instituto de Pesquisas Clinicas
Brasília, 70.200-730, Brazil
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Lanzhou University Second Hospital
Lanzhou, 730031, China
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London Health Sciences Centre
London, Ontario, N6A 5A5, Canada
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States
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Medical Associates Research Group, Inc.
San Diego, California, 92123, United States
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Medical Network Spolka z o.o. WIP Warsaw IBD Point Profesor Kierkus
Warsaw, 04 501, Poland
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Medizinische Hochschule Hannover
Hanover, 30625, Germany
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Melita Medical Sp. z o.o.
Wroclaw, 53 611, Poland
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Mercy Medical Center
Baltimore, Maryland, 21202-2102, United States
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Mersin University Medical Faculty
Mersin, 33343, Turkey (Türkiye)
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Midas Hospital
Nagpur, 441108, India
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Mie University Hospital
Tsu, 514 8507, Japan
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Nanjing Drum Tower Hospital
Nanjing, 210008, China
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National Hospital Organization Shizuoka Medical Center
Shimizu, 411-8611, Japan
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Nemocnice Ceske Budejovice
České Budějovice, 370 01, Czechia
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Nemocnice Slany
Slaný, 27401, Czechia
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New York Gastroenterology Associates
New York, New York, 10075, United States
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Northshore Gastroenterology Research, LLC
Westlake, Ohio, 44145, United States
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Ochsner Medical Center
Jefferson, Louisiana, 70121, United States
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Ospedale Sacro Cuore Don Calabria
Negrar, 37024, Italy
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Ospedale San Raffaele di Milano
Milan, 20132, Italy
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Oxford University Hospitals NHS Foundation Trust
Oxford, OX3 9DU, United Kingdom
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Pannónia Magánorvosi Centrum Kft
Budapest, H-1136, Hungary
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Peak Gastroenterology Associates
Colorado Springs, Colorado, 80907, United States
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Pesquisare Saude
Santo André, 09080-110, Brazil
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Qilu Hospital of Shandong University
Jinan, 250012, China
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S C Delta Health Care S R L
Bucharest, 014146, Romania
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S. R. Kalla Memorial General Hospital
Jaipur, 302006, India
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SIDS Hospital & Research Centre
Surat, 395002, India
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Sai Gastroenterology Proctology
Fujiidera-shi, 583-0027, Japan
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Samsung Medical Center
Seoul, 06351, South Korea
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Sanatorio 9 de Julio
San Miguel de Tucumán, 4000, Argentina
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Sapporo Higashi Tokushukai Hospital
Sapporo, 065-0033, Japan
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Sapporo Tokushukai Hospital
Sapporo, 004-0041, Japan
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Semmelweis Egyetem
Budapest, 1083, Hungary
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Semmelweis Egyetem
Budapest, 1088, Hungary
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Seoul National University Hospital
Seoul, 03080, South Korea
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Shengjing Hospital Of China Medical University
Shenyang, 110022, China
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Sir Run Run Shaw Hospital Zhejiang University School of Medicine
Hangzhou, 310000, China
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Sonomed Sp. z o.o.
Szczecin, 71-685, Poland
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Southampton University Hospital
Southampton, SO16 6YD, United Kingdom
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Southern Star Research Institute, LLC
San Antonio, Texas, 78229, United States
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Spital Memorial
Bucharest, 013823, Romania
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St Georges University Hospital NHS Foundation Trust
London, SW17 0RE, United Kingdom
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Staedtisches Klinikum Lueneburg
Lüneburg, 21339, Germany
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Sultan Idris Shah Hospital
Kajang, 43000, Malaysia
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Sunshine Coast University Hospital
Birtinya, 4575, Australia
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Tandem Clinical Research
Marrero, Louisiana, 70072, United States
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The Catholic university of Korea, St. Vincent's Hospital
Suwon, 16247, South Korea
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The First Affiliated Hospital Sun Yat sen University
Guangzhou, 510060, China
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The Second Affiliated Hospital of Air Force Medical University - Tangdu Hospital
Xi'an, 710038, China
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The Sixth Affiliated Hospital Sun Yat sen University
Guangzhou, 510655, China
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The second Xiangya Hospital of Central South University
Changsha, 410011, China
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Toho University Sakura Medical Center
Sakura, 285-8741, Japan
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Tokyo Metropolitan Bokutoh Hospital
Sumida Ku, 130 8575, Japan
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Tsujinaka Hospital Kashiwanoha
Kashiwa, 277-0871, Japan
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Tyler Research Institute, LLC
Tyler, Texas, 75701, United States
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UNC Hospitals
Chapel Hill, North Carolina, 27514, United States
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UNESP - Faculdade de Medicina da Universidade Estadual Paulista - Campus Botucatu
Botucatu, 18618-687, Brazil
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Uludag Universitesi Tıp Fakultesi Hastanesi
Bursa, 16059, Turkey (Türkiye)
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Union Hospital Tongji Medical College of Huazhong University of Science and Technology
Wuhan, 430022, China
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Universitaetsklinikum Carl Gustav Carus TU Dresden
Dresden, 01307, Germany
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Universitair Ziekenhuis Leuven
Leuven, 3000, Belgium
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Universitatsklinikum Schleswig Holstein Kiel
Kiel, 24105, Germany
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University Malaya Medical Centre
Kuala Lumpur, 59100, Malaysia
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Vasutegeszsegugyi Nonprofit Kozhasznu Kft
Debrecen, 4025, Hungary
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Vitaz
Sint-Niklaas, 9100, Belgium
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Washington Gastroenterology, PLLC
Bellevue, Washington, 98004, United States
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Washington Gastroenterology, PLLC
Tacoma, Washington, 98405, United States
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Whiston Hospital
Prescot, L35 5DR, United Kingdom
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Wollongong Private Hospital
Wollongong, 2500, Australia
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Wuxi People s Hospital
Wuxi, 214023, China
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Yeungnam University Hospital
Daegu, 42415, South Korea
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Yokohama City University Medical Center
Yokohama, 232 0024, Japan
Conditions
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