Nanoparticle drug aims to wake up immune system against tumors

NCT ID NCT07605962

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called UI-102, which is a tiny nanoparticle designed to activate the immune system to fight cancer. It is for people with advanced solid tumors that have not responded to standard treatments. The trial will enroll 140 participants to first find the safest dose, then see if it can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

UI-102 (a nanoparticle that activates the immune system to attack tumors)

What this could lead to

If successful, this could lead to a new immunotherapy option for people with advanced solid tumors that have not responded to standard treatments.

What could go wrong

This is an early phase 1/2 trial with a small number of participants, so safety and effectiveness are not yet proven. Immune activation can also cause side effects like flu-like symptoms or inflammation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NEXT Oncology

    RECRUITING

    Dallas, Texas, 75039, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology

    RECRUITING

    Houston, Texas, 77054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••