New hope for Hard-to-Treat ovarian cancer: drug combo trial launches

NCT ID NCT07637851

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests a new drug, ubamatamab, combined with standard chemotherapy drugs (carboplatin, paclitaxel, and bevacizumab) in 43 people with advanced ovarian cancer that did not respond well to initial treatment. The goal is to see if the combination is safe and can shrink tumors. Participants will receive three cycles of the combination, then maintenance therapy for up to 15 months.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre François Baclesse

    Caen, 14076, France

  • Centre Georges François Leclerc

    Dijon, 21079, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Gustave Roussy

    Villejuif, 94805, France

  • HCL - Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Hôpital de Hautepierre

    Strasbourg, 67098, France

  • ICM Val d'Aurelle

    Montpellier, 34298, France

  • ICO - Centre René Gauducheau

    Saint-Herblain, 44805, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.