New hope for Hard-to-Treat ovarian cancer: drug combo trial launches
NCT ID NCT07637851
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests a new drug, ubamatamab, combined with standard chemotherapy drugs (carboplatin, paclitaxel, and bevacizumab) in 43 people with advanced ovarian cancer that did not respond well to initial treatment. The goal is to see if the combination is safe and can shrink tumors. Participants will receive three cycles of the combination, then maintenance therapy for up to 15 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Eugène Marquis
Rennes, 35042, France
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Centre François Baclesse
Caen, 14076, France
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Centre Georges François Leclerc
Dijon, 21079, France
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Centre Léon Bérard
Lyon, 69373, France
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Gustave Roussy
Villejuif, 94805, France
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HCL - Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
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Hôpital de Hautepierre
Strasbourg, 67098, France
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ICM Val d'Aurelle
Montpellier, 34298, France
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ICO - Centre René Gauducheau
Saint-Herblain, 44805, France
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Institut Bergonié
Bordeaux, 33076, France
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Institut Paoli Calmettes
Marseille, 13273, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug combo revive Immunotherapy's power against resistant tumors?
- Can heated chemotherapy improve ovarian cancer outcomes?
- Can a new PET tracer light up hidden cancers?
- A Two-for-One surgery: could tube removal during Weight-Loss surgery slash ovarian cancer risk?
- Can AI spot ovarian cancer on CT scans before It's too late?
- Can Lab-Grown tumors unlock the secrets of ovarian cancer resistance?