Reading Cancer's genetic playbook: a quest to match patients to the right experimental therapy

NCT ID NCT07737509

Recruiting now Knowledge-focused Sponsor: Institute of Cancer Research, United Kingdom Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This observational study aims to identify genetic mutations in adults with advanced solid cancers who are being considered for or are already in early-phase clinical trials. By analyzing tumor and blood samples over time, researchers hope to understand how these mutations influence cancer growth, treatment response, and resistance. The goal is to use this genetic information to better match patients to suitable trials and support the development of more personalized cancer treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help doctors select the right early-phase clinical trial for each patient based on their tumor's genetic profile, and may uncover new targets for cancer drugs.
What could go wrong: This is an observational study, not a treatment trial, so it will not directly benefit participants. The findings may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMOURS

Contacts and locations

Locations

Royal Marsden NHS Foundation Trust - Drug Development Unit
RECRUITING

Sutton, SM2 5PT, United Kingdom
Royal Marsden NHS Foundation Trust - Prostate Cancer Targeted Therapy Group
RECRUITING

Sutton, SM2 5PT, United Kingdom

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