New drug shows promise for Crohn's sufferers

NCT ID NCT05013905

Completed Disease control Sponsor: Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) Source: ClinicalTrials.gov ↗

First seen Apr 25, 2026 · Last updated May 13, 2026 · Updated 4 times

Summary

This study tested a new drug called tulisokibart (PRA023) in 55 people with moderate to severe Crohn's disease. The goal was to see if the drug is safe and can improve symptoms and gut healing. Participants who finished the first 12 weeks could continue treatment for up to 170 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Prometheus Biosciences Selected Center

Krakow, 31-501, Poland
Prometheus Biosciences Selected Center

Warsaw, 00-635, Poland
Prometheus Biosciences Selected Center

Warsaw, 52-416, Poland
Prometheus Biosciences Selected Site

Los Angeles, California, 90045, United States
Prometheus Biosciences Selected Site

Los Angeles, California, 90048, United States
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Liberty, Kansas, 64098, United States
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Chesterfield, Michigan, 48047, United States
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Ypsilanti, Michigan, 48197, United States
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St Louis, Missouri, 63141, United States
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Lebanon, New Hampshire, 03756, United States
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New York, New York, 10065, United States
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Garland, Texas, 75044, United States
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Lubbock, Texas, 79410, United States
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Lubbock, Texas, 79424, United States
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San Antonio, Texas, 78229, United States
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Southlake, Texas, 78229, United States
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Tyler, Texas, 75702, United States
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Bellevue, Washington, 98004, United States
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Tacoma, Washington, 98405, United States
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Bankstown, New South Wales, 2146, Australia
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Woolloongabba, Queensland, 4102, Australia
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Adelaide, South Australia, 5000, Australia
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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London, Ontario, N6A 5W9, Canada
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Brno, Czechia
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Slaný, 274 01, Czechia
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Clichy, 92110, France
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Nice, 06202, France
Prometheus Biosciences Selected Site

Saint-Priest-en-Jarez, 42270, France
Prometheus Biosciences Selected Site

Vandœuvre-lès-Nancy, 54511, France
Prometheus Biosciences Selected Site

Tbilisi, Georgia
Prometheus Biosciences Selected Site

Rzeszów, 35-326, Poland
Prometheus Biosciences Selected Site

Sopot, 81-756, Poland
Prometheus Biosciences Selected Site

Torun, 87-100, Poland
Prometheus Biosciences Selected Site

Warsaw, 03-580, Poland
Prometheus Biosciences Selected Site

Wroclaw, 52-416, Poland

Conditions

Explore the condition pages connected to this study.

CROHN DISEASE