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New drug shows promise for spine arthritis pain

NCT ID NCT07133633

Recruiting now Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests a new medicine called tulisokibart for people with radiographic axial spondyloarthritis, a type of arthritis that causes pain and stiffness in the spine and hips. Researchers want to see if different doses can improve symptoms better than a placebo. About 315 adults with active disease will take part over 16 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AARA Arizona Arthritis & Rheumatology Associates, P.C. - Glendale ( Site 0056)

    RECRUITING

    Glendale, Arizona, 85306, United States

    Contact Phone: •••-•••-••••

  • AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Chandler ( Site 0036)

    RECRUITING

    Chandler, Arizona, 85225, United States

    Contact Phone: •••-•••-••••

  • AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Flagstaff ( Site 0021)

    RECRUITING

    Flagstaff, Arizona, 86001, United States

    Contact Phone: •••-•••-••••

  • AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Irving ( Site 0032)

    RECRUITING

    Irving, Texas, 75039, United States

    Contact Phone: •••-•••-••••

  • AARA Clinical Research - Murfreesboro Medical Clinic ( Site 0029)

    RECRUITING

    Murfreesboro, Tennessee, 37128, United States

    Contact Phone: •••-•••-••••

  • ANKARA UNIVERSITY IBNI SINA HOSPITAL ( Site 1600)

    RECRUITING

    Ankara, 06230, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Advanced Rheumatology of Houston ( Site 0001)

    RECRUITING

    The Woodlands, Texas, 77382, United States

    Contact Phone: •••-•••-••••

  • Altoona Center for Clinical Research ( Site 0004)

    RECRUITING

    Duncansville, Pennsylvania, 16635, United States

    Contact Phone: •••-•••-••••

  • Amsterdam UMC ( Site 1101)

    RECRUITING

    Amsterdam, North Holland, 1081 HV, Netherlands

    Contact Phone: •••-•••-••••

  • Arizona Arthritis & Rheumatology Associates, P.C. - Gilbert ( Site 0022)

    RECRUITING

    Gilbert, Arizona, 85297, United States

    Contact Phone: •••-•••-••••

  • Arizona Arthritis & Rheumatology Associates, P.C. - Tucson ( Site 0025)

    RECRUITING

    Tucson, Arizona, 85704-1140, United States

    Contact Phone: •••-•••-••••

  • Arthritis Care of Texas ( Site 0048)

    RECRUITING

    Corpus Christi, Texas, 78415, United States

    Contact Phone: •••-•••-••••

  • Arthritis and Rheumatic Disease Specialties ( Site 0016)

    RECRUITING

    Aventura, Florida, 33180, United States

    Contact Phone: •••-•••-••••

  • Arthritis and Rheumatism Associates - Rockville ( Site 0019)

    RECRUITING

    Rockville, Maryland, 20850, United States

    Contact Phone: •••-•••-••••

  • Barnet Hospital ( Site 1806)

    RECRUITING

    Barnet, EN5 3DJ, United Kingdom

    Contact Phone: •••-•••-••••

  • Bay Area Arthritis and Osteoporosis ( Site 0041)

    RECRUITING

    Brandon, Florida, 33511, United States

    Contact Phone: •••-•••-••••

  • Bioreuma ( Site 2109)

    RECRUITING

    Concepción, Biobio, 4070280, Chile

    Contact Phone: •••-•••-••••

  • Bradfordhill ( Site 2110)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

    Contact Phone: •••-•••-••••

  • CIREEM SAS ( Site 2204)

    ACTIVE_NOT_RECRUITING

    Bogota, Cundinamarca, 110221, Colombia

  • CMIP-CENTRO MINEIRO DE PESQUISA ( Site 1999)

    RECRUITING

    Juiz de Fora, Minas Gerais, 36010-570, Brazil

    Contact Phone: •••-•••-••••

  • Centre de Recherche Musculo-Squelettique ( Site 0202)

    RECRUITING

    Trois-Rivières, Quebec, G9A 3Y2, Canada

    Contact Phone: •••-•••-••••

  • Centro de Estudios GyC ( Site 2103)

    RECRUITING

    Santiago, Region M. de Santiago, 7500504, Chile

    Contact Phone: •••-•••-••••

  • Centro de Pesquisas Clínicas do Hospital das Clínicas de São Paulo ( Site 1992)

    RECRUITING

    São Paulo, 05403-000, Brazil

    Contact Phone: •••-•••-••••

  • Chang Gung Memorial Hospital - Linkou Branch ( Site 2904)

    RECRUITING

    Taoyuan, 33305, Taiwan

    Contact Phone: •••-•••-••••

  • Chang Gung Memorial Hospital at Kaohsiung ( Site 2908)

    RECRUITING

    Kaohsiung City, 833, Taiwan

    Contact Phone: •••-•••-••••

  • Charite Universitätsmedizin Berlin Campus Benjamin Franklin-Medizinische Klinik I für Gastroenterol ( Site 0601)

    RECRUITING

    Berlin, 12203, Germany

    Contact Phone: •••-•••-••••

  • Chicago Arthritis & Regenerative Medicine ( Site 0042)

    RECRUITING

    Chicago, Illinois, 60661, United States

    Contact Phone: •••-•••-••••

  • Chinese Academy of Medical Science Peking Union Medical College Hospital ( Site 3100)

    RECRUITING

    Beijing, Beijing Municipality, 100005, China

    Contact Phone: •••-•••-••••

  • Clinica Alemana Osorno ( Site 2114)

    RECRUITING

    Osorno, Los Lagos Region, 5311089, Chile

    Contact Phone: •••-•••-••••

  • Clinica de la Costa S.A.S. ( Site 2202)

    RECRUITING

    Barranquilla, Atlántico, 080020, Colombia

    Contact Phone: •••-•••-••••

  • Cohen Medical Centers ( Site 0034)

    RECRUITING

    Thousand Oaks, California, 91360-3967, United States

    Contact Phone: •••-•••-••••

  • Communal Nonprofit Enterprise Cherkasy Regional Hospital of Cherkasy Oblast Council ( Site 1704)

    RECRUITING

    Cherkasy, Chernivetska Oblast, 18009, Ukraine

    Contact Phone: •••-•••-••••

  • Complexo Hospital de Clínicas da Universidade Federal do Paraná ( Site 1991)

    RECRUITING

    Curitiba, Paraná, 80060-900, Brazil

    Contact Phone: •••-•••-••••

  • DM Clinical Research - TRA ( Site 0010)

    RECRUITING

    Tomball, Texas, 77375, United States

    Contact Phone: •••-•••-••••

  • Enroll SpA ( Site 2101)

    RECRUITING

    Santiago, Region M. de Santiago, 7500587, Chile

    Contact Phone: •••-•••-••••

  • Epic Medical Research ( Site 0061)

    RECRUITING

    Red Oak, Texas, 75154, United States

    Contact Phone: •••-•••-••••

  • First Affiliated Hospital of Kunming Medical University ( Site 3123)

    RECRUITING

    Kunming, Yunnan, 650032, China

    Contact Phone: •••-•••-••••

  • Fundación Valle del Lili ( Site 2201)

    RECRUITING

    Cali, Valle del Cauca Department, 760032, Colombia

    Contact Phone: •••-•••-••••

  • G.R.M.O. (Groupe de recherche en maladies osseuses) Inc. ( Site 0200)

    RECRUITING

    Québec, Quebec, G1V 3M7, Canada

    Contact Phone: •••-•••-••••

  • GNP Research - Hollywood ( Site 0020)

    RECRUITING

    Cooper City, Florida, 33024, United States

    Contact Phone: •••-•••-••••

  • Guangdong Provincial People's Hospital ( Site 3110)

    RECRUITING

    Guangzhou, Guangdong, 510080, China

    Contact Phone: •••-•••-••••

  • HRF II - Hamburger Rheuma Forschungszentrum II MVZ für Rheumatologie und Autoimmunmedizin Hamburg G ( Site 0604)

    RECRUITING

    Hamburg, 20095, Germany

    Contact Phone: •••-•••-••••

  • Hacettepe Universite Hastaneleri ( Site 1603)

    RECRUITING

    Ankara, 06230, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Hanyang University Seoul Hospital ( Site 2800)

    RECRUITING

    Seoul, 04763, South Korea

    Contact Phone: •••-•••-••••

  • IBPClin - Instituto Brasil de Pesquisa Clínica ( Site 1994)

    RECRUITING

    Rio de Janeiro, 20241-180, Brazil

    Contact Phone: •••-•••-••••

  • Inland Rheumatology Clinical Trials, Inc. ( Site 0002)

    RECRUITING

    Upland, California, 91786, United States

    Contact Phone: •••-•••-••••

  • Innovation Medical Research Center ( Site 0012)

    RECRUITING

    Palmetto Bay, Florida, 33157, United States

    Contact Phone: •••-•••-••••

  • Inspire Santa Fe Medical Group ( Site 0011)

    RECRUITING

    Santa Fe, New Mexico, 87505, United States

    Contact Phone: •••-•••-••••

  • Istanbul University Cerrahpasa Medical School Internal Diseases Institute ( Site 1604)

    RECRUITING

    Fatih, Istanbul, 34098, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Kansas City Physician Partners ( Site 0027)

    RECRUITING

    Kansas City, Missouri, 64111, United States

    Contact Phone: •••-•••-••••

  • Kaohsiung Veterans General Hospital ( Site 2905)

    RECRUITING

    Kaohsiung City, 813414, Taiwan

    Contact Phone: •••-•••-••••

  • Kocaeli Üniversitesi ( Site 1605)

    RECRUITING

    Kocaeli, 41380, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Konya Necmettin Erbakan Universitesi ( Site 1606)

    RECRUITING

    Konya, 42090, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Kyiv Railway Clinical Hospital No.2 of Branch Health Center of the Public Joint Stock Company Ukrain ( Site 1701)

    RECRUITING

    Kyiv, 03049, Ukraine

    Contact Phone: •••-•••-••••

  • Kyung Hee University Hosptial at Gangdong ( Site 2802)

    RECRUITING

    Seoul, 05278, South Korea

    Contact Phone: •••-•••-••••

  • LMK Serviços Médicos S/S ( Site 2000)

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90480-000, Brazil

    Contact Phone: •••-•••-••••

  • Lone Star Arthritis & Rheumatology Associates, P.C. ( Site 0028)

    RECRUITING

    Fort Worth, Texas, 76109, United States

    Contact Phone: •••-•••-••••

  • Lviv Clin Hospital of Planned Treatment Rehabilitation Palliative Care ( Site 1710)

    RECRUITING

    Lviv, Lviv Oblast, 79011, Ukraine

    Contact Phone: •••-•••-••••

  • ME "Ternopil Regional Clinical Hospital of Ternopil Regional Council" ( Site 1707)

    RECRUITING

    Ternopil, Ternopil Oblast, 46002, Ukraine

    Contact Phone: •••-•••-••••

  • MICS Centrum Medyczne Bydgoszcz ( Site 1206)

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-065, Poland

    Contact Phone: •••-•••-••••

  • MICS Centrum Medyczne Torun ( Site 1202)

    RECRUITING

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

    Contact Phone: •••-•••-••••

  • MICS Centrum Medyczne Warszawa ( Site 1204)

    RECRUITING

    Warsaw, Masovian Voivodeship, 00-874, Poland

    Contact Phone: •••-•••-••••

  • Maasstad Ziekenhuis ( Site 1102)

    RECRUITING

    Rotterdam, South Holland, 3079DZ, Netherlands

    Contact Phone: •••-•••-••••

  • Medical Center "Universal Clinic "Oberig" of Limited Liability Company "Kapytal" ( Site 1706)

    RECRUITING

    Kyiv, 03057, Ukraine

    Contact Phone: •••-•••-••••

  • Medical Center of Limited Liability Company "Medical Center "Consilium Medical" ( Site 1715)

    RECRUITING

    Kyiv, Kyivska Oblast, 04050, Ukraine

    Contact Phone: •••-•••-••••

  • Medicover München Ost MVZ ( Site 0611)

    RECRUITING

    Munich, Bavaria, 81667, Germany

    Contact Phone: •••-•••-••••

  • Municipal Non-Profit Enterprise "Khmelnytskyi Regional Hospital" of Khmelnytskyi Regional Council ( Site 1713)

    RECRUITING

    Khmelnytskiy, Khmelnytskyi Oblast, 29000, Ukraine

    Contact Phone: •••-•••-••••

  • Municipal Nonprofit Enterprise "Vinnytsia Regional Clinical Hospital n.a. M. I. Pyrohov of Vinnytsia ( Site 1700)

    RECRUITING

    Vinnytsa, Vinnytsia Oblast, 21018, Ukraine

    Contact Phone: •••-•••-••••

  • Municipal Public Non-Profit Enterprise "City Clinical Hospital №1 of the Ivano-Frankivsk City Counc ( Site 1705)

    RECRUITING

    Ukraine, Ivano-Frankivsk Oblast, 76018, Ukraine

    Contact Phone: •••-•••-••••

  • Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im.Prof. El. Reicher-ul.Spartanska 1 ( Site 1205)

    RECRUITING

    Warsaw, Masovian Voivodeship, 02-637, Poland

    Contact Phone: •••-•••-••••

  • National Cheng Kung University Hospital ( Site 2903)

    RECRUITING

    Tainan, 704, Taiwan

    Contact Phone: •••-•••-••••

  • National Taiwan University Hospital ( Site 2902)

    RECRUITING

    Taipei City, Taipei, 100, Taiwan

    Contact Phone: •••-•••-••••

  • Newport Huntington Medical Group ( Site 0005)

    RECRUITING

    Huntington Beach, California, 92648, United States

    Contact Phone: •••-•••-••••

  • Norfolk & Norwich University Hospital NHS Foundation Trust ( Site 1800)

    RECRUITING

    Norwich, Norfolk, NR4 7UY, United Kingdom

    Contact Phone: •••-•••-••••

  • PEOPLE'S HOSPITAL OF XINJIANG UYGUR AUTONOMOUS REGION ( Site 3124)

    RECRUITING

    Ürümqi, Xinjiang, 830001, China

    Contact Phone: •••-•••-••••

  • Perelman Center for Advanced Medicine ( Site 0060)

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-••••

  • Physician Research Collaboration, LLC ( Site 0057)

    RECRUITING

    Lincoln, Nebraska, 68516-5497, United States

    Contact Phone: •••-•••-••••

  • Pingxiang People's Hospital ( Site 3115)

    RECRUITING

    Pingxiang, Jiangxi, 337055, China

    Contact Phone: •••-•••-••••

  • Provecta Research Network LLC ( Site 0054)

    RECRUITING

    Houston, Texas, 77027, United States

    Contact Phone: •••-•••-••••

  • Providence Medical Foundation ( Site 0049)

    RECRUITING

    Fullerton, California, 92835, United States

    Contact Phone: •••-•••-••••

  • Rheumatologische Schwerpunktpraxis ( Site 0605)

    RECRUITING

    Berlin, 12161, Germany

    Contact Phone: •••-•••-••••

  • Rheumatology Associates ( Site 0055)

    RECRUITING

    Arlington, Texas, 76012, United States

    Contact Phone: •••-•••-••••

  • Rheumazentrum Ratingen Studienambulanz ( Site 0602)

    RECRUITING

    Ratingen, North Rhine-Westphalia, 40878, Germany

    Contact Phone: •••-•••-••••

  • Rheumazentrum Ruhrgebiet ( Site 0600)

    RECRUITING

    Herne, North Rhine-Westphalia, 44649, Germany

    Contact Phone: •••-•••-••••

  • Royal United Hospital Bath NHS Foundation Trust ( Site 1803)

    RECRUITING

    Bath, Somerset, BA1 3NG, United Kingdom

    Contact Phone: •••-•••-••••

  • St Luke's Hospital ( Site 1801)

    RECRUITING

    Bradford, BD5 0NA, United Kingdom

    Contact Phone: •••-•••-••••

  • Szpital Uniwersytecki Nr 2 im. dr J. Biziela w Bydgoszczy ( Site 1203)

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-168, Poland

    Contact Phone: •••-•••-••••

  • Taipei Medical University Shuang Ho Hospital ( Site 2900)

    RECRUITING

    New Taipei City, New Taipei, 235, Taiwan

    Contact Phone: •••-•••-••••

  • Taipei Veterans General Hospital ( Site 2906)

    RECRUITING

    Taipei, 112, Taiwan

    Contact Phone: •••-•••-••••

  • The First Affiliated Hospital of Henan University of Science &Technology ( Site 3121)

    RECRUITING

    Luoyang, Henan, 471003, China

    Contact Phone: •••-•••-••••

  • The First Afflilated Hospital of Bengbu Medical College ( Site 3119)

    RECRUITING

    Bengbu, Anhui, 233004, China

    Contact Phone: •••-•••-••••

  • The First Hospital Of Jilin University ( Site 3103)

    RECRUITING

    Changchun, Jilin, 130021, China

    Contact Phone: •••-•••-••••

  • The Third Affiliated Hospital of Sun Yat-Sen University ( Site 3114)

    RECRUITING

    Guangzhou, Guangdong, 510630, China

    Contact Phone: •••-•••-••••

  • TriWest Research Associates - Chula Vista ( Site 0013)

    RECRUITING

    Chula Vista, California, 91910, United States

    Contact Phone: •••-•••-••••

  • Velocity Clinical Research - West County Rheumatology, St. Louis ( Site 0038)

    RECRUITING

    St Louis, Missouri, 63131, United States

    Contact Phone: •••-•••-••••

  • Willow Rheumatology and Wellness, PLLC ( Site 0035)

    RECRUITING

    Willowbrook, Illinois, 60527, United States

    Contact Phone: •••-•••-••••

  • Zespół Poradni Specjalistycznych Reumed Filia nr 1 Wallenroda ( Site 1201)

    RECRUITING

    Lublin, Lublin Voivodeship, 20-607, Poland

    Contact Phone: •••-•••-••••

  • Zuyderland Medical Centre ( Site 1100)

    RECRUITING

    Heerlen, Limburg, 6419 PC, Netherlands

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS