New triple therapy aims to outsmart Hard-to-Treat colorectal cancer

NCT ID NCT06497985

First seen Apr 05, 2026 · Last updated May 16, 2026 · Updated 9 times

Summary

This study tests a new combination of three drugs (tucidinostat, sintilimab, and bevacizumab) against a standard single drug (fruquintinib) in people with a common type of advanced colorectal cancer that has not responded to at least two prior treatments. The goal is to see if the combination helps patients live longer. About 430 adults aged 18 to 75 with MSS/pMMR colorectal cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rui-Hua Xu

    RECRUITING

    Guangzhou, Guangdong, 510050, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.