New drug combo aims to keep breast cancer from returning to the brain

NCT ID NCT05323955

Summary

This study is for people with advanced HER2+ breast cancer whose cancer has spread to the brain but is stable elsewhere. It tests if adding the drug tucatinib to their current standard treatment can help keep the brain tumors from growing back longer. About 48 participants will receive the new combination and be monitored to see how long their brain disease stays controlled and to check for side effects.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63130, United States

Conditions

Explore the condition pages connected to this study.