Engineered immune cells target hidden colorectal cancer

NCT ID NCT06358430

First seen Nov 19, 2025 · Last updated Apr 24, 2026 · Updated 19 times

Summary

This early-phase trial tests a combination of specially engineered immune cells (TROP2-CAR-NK cells) and a targeted drug (cetuximab) in adults with colorectal cancer that has minimal residual disease—meaning small amounts of cancer remain after treatment. The main goal is to find a safe dose and check for side effects. About 42 participants will take part in this study at M.D. Anderson Cancer Center.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.