New Triple-Action antibody takes on tough blood cancers

NCT ID NCT05652335

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 28 times

Summary

This early-phase study tests an experimental drug called JNJ-79635322, a trispecific antibody designed to attack cancer cells in multiple ways. It is for people with multiple myeloma or AL amyloidosis that has returned or not responded to prior treatments. The main goals are to find a safe dose and check for side effects in about 180 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Lyon Sud

    RECRUITING

    Pierre-Bénite, 69495, France

  • CHU Nantes

    RECRUITING

    Nantes, 44093, France

  • CHU de Liege

    RECRUITING

    Liège, 4000, Belgium

  • Chu Rennes Hopital Pontchaillou

    COMPLETED

    Rennes, 35000, France

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • City of Hope Orange County Lennar Foundation Cancer Center

    RECRUITING

    Irvine, California, 92618, United States

  • Clinica Univ. de Navarra

    RECRUITING

    Pamplona, 31008, Spain

  • Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

  • Hosp Clinic de Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hosp Clinico Univ de Salamanca

    RECRUITING

    Salamanca, 37007, Spain

  • Hosp Univ Fund Jimenez Diaz

    RECRUITING

    Madrid, 28040, Spain

  • Hosp. Univ. Germans Trias I Pujol

    RECRUITING

    Badalona, 08916, Spain

  • Icahn School of Medicine at Mt. Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Institut Claudius Regaud

    RECRUITING

    Toulouse, 31100, France

  • Japanese Red Cross Medical Center

    ACTIVE_NOT_RECRUITING

    Shibuya City, 150-8935, Japan

  • Levine Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28001, United States

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Osaka University Hospital

    ACTIVE_NOT_RECRUITING

    Suita-shi, 565-0871, Japan

  • Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • The Cancer Institute Hospital of JFCR

    COMPLETED

    Tokyo, 135-8550, Japan

  • UMC Utrecht

    RECRUITING

    Utrecht, 3584 CX, Netherlands

  • UZ Antwerpen

    RECRUITING

    Edegem, 2650, Belgium

  • UZ Gent

    RECRUITING

    Ghent, 9000, Belgium

  • Universitair Medisch Centrum Groningen

    RECRUITING

    Groningen, 9713 GZ, Netherlands

  • University College Hospital

    RECRUITING

    London, W1T 7HA, United Kingdom

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

  • University of Pennsylvania Division of Hematology Oncology Perelman Center for Advanced Medicine

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • VUMC Amsterdam

    RECRUITING

    Amsterdam, 1081 HV, Netherlands

Conditions

Explore the condition pages connected to this study.