Ancient herb meets modern science: can trishul fight rectal cancer?

NCT ID NCT07430696

Not yet recruiting Disease control Sponsor: University of Kelaniya Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether an Ayurvedic drug called Trishul can help shrink rectal tumors and improve survival. Forty adults with advanced rectal cancer will receive either Trishul or a placebo pill, in addition to their standard treatment (chemo-radiation and surgery). The study is double-blind and placebo-controlled, meaning neither patients nor doctors know who gets the real drug. The main goal is to see if Trishul improves overall survival and disease-free survival over 24 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Trishul (Ayurvedic drug)
What this could lead to: If it works, this could point toward a safe, plant-based add-on treatment to improve survival in rectal cancer.
What could go wrong: This is a very small early pilot study (40 people). The drug is unproven, and results may show no benefit over placebo. Side effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EFFICACY OF TRISHUL

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