New triplet therapy targets Hard-to-Treat bladder cancer in small trial
NCT ID NCT05335941
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 17 times
Summary
This study tests a combination of three drugs (pemetrexed, etrumadenant, and zimberelimab) in 10 adults with advanced bladder cancer that has a specific genetic change called MTAP deficiency. All participants had already received immunotherapy. The goal is to see if the triplet therapy can shrink tumors or control the disease, while monitoring side effects. The trial is only at MD Anderson Cancer Center.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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