Breakthrough pill cuts risk of deadly second stroke

NCT ID NCT02699645

Completed Prevention Sponsor: The George Institute Source: ClinicalTrials.gov ↗

Summary

This large international trial tested whether a combination of three low-dose blood pressure medicines (a 'Triple Pill') could prevent a second stroke in people who had already survived a serious type of stroke caused by bleeding in the brain. Over 1,600 participants were randomly assigned to take either the Triple Pill or a placebo pill on top of their usual care. The goal was to see if this more intensive approach to lowering blood pressure was safe and could reduce the risk of having another stroke.

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Contacts and locations

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Locations

Ahmadu Bello University Teaching Hospital

Zaria, Nigeria
Chiayi Chang Gung Memorial Hospital

Chiayi City, Taiwan
Clínica Neurológica e Neurocirurgica de Joinville

Joinville, Brazil
Colombo North Teaching Hospital

Colombo, Sri Lanka
Fiona Stanley Hospital

Murdoch, Western Australia, 6150, Australia
Gampaha District General Hospital

Gampaha, 11000, Sri Lanka
Hospital Geral de Fortaleza

Fortaleza, Brazil
Hospital Moinhos de Vento

Porto Alegre, Brazil
Hospital Queen Elizabeth

Kota Kinabalu, Malaysia
Hospital Seberang Jaya

Pulau Pinang, Malaysia
Hospital Universiti Sains Malaysia

Kubang Kerian, Malaysia
Hospital da Bahia

Salvador, Brazil
Hospital das Clínicas de Botucatu

Botucatu, Brazil
Hospital das Clínicas de Porto Alegre

Porto Alegre, Brazil
Hospital das Clínicas de Ribeirão Preto

Ribeirão Preto, Brazil
Hospital de Base São José do Rio Preto

Rio Prêto, Brazil
Instituto Flumignano de Medicina

Curitiba, Brazil
Jaffna Teaching Hospital

Jaffna, 40000, Sri Lanka
Jos University Teaching Hospital

Jos, Nigeria
Kalubowila (Colombo South) Teaching Hospital

Colombo, Sri Lanka
Kandy Teaching Hospital

Kandy, Kandy, 20000, Sri Lanka
Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, 833, Taiwan
Karapitiya Teaching Hospital

Galle, Sri Lanka
LTD Pineo Medical Ecosystem

Tbilisi, 0112, Georgia
LTD S. Khechinashvili University Hospital

Tbilisi, 0179, Georgia
LTD Urgent Neurological Clinic "Neurology"

Tbilisi, 0144, Georgia
Lagos University Teaching Hospital, Lagos

Lagos, Nigeria
Linkou Chang Gung Memorial Hospital

Taoyuan District, 333, Taiwan
Liverpool Hospital

Liverpool, New South Wales, 2170, Australia
Maastricht University Medical Center

Maastricht, Netherlands
Morriston Hospital

Swansea, SA6 6NL, United Kingdom
National Hospital of Sri Lanka

Colombo, Sri Lanka
National University Hospital

Singapore, Singapore
Nottingham City Hospital

Nottingham, NG5 1PB, United Kingdom
Peradeniya Teaching Hospital

Peradeniya, Sri Lanka
Port Macquarie Base Hospital

Port Macquarie, New South Wales, 2444, Australia
Princess Alexandra Hospital

Woolloongabba, Queensland, 4102, Australia
Queen Elizabeth University Hospital

Glasgow, G51 4TF, United Kingdom
Radboud University Medical Center

Nijmegen, 6525 GC, Netherlands
Ragama Teaching Hospital

Ragama, Ragama, 11010, Sri Lanka
Royal Devon & Exeter Hospital

Exeter, EX2 5DW, United Kingdom
Royal Hallamshire Hospital

Sheffield, S10 2JF, United Kingdom
Royal Infirmary Edinburgh

Edinburgh, EH16 4SB, United Kingdom
Royal Melbourne Hospital

Melbourne, Victoria, 3050, Australia
Royal Prince Alfred Hospital

Sydney, New South Wales, 2050, Australia
Royal Stoke University Hospital

Stoke-on-Trent, T4 6QG, United Kingdom
Salford Royal Hospital

Salford, M6 8HD, United Kingdom
Sarawak General Hospital

Kuching, Malaysia
Sri Jayewardenepura General Hospital

Nugegoda, Sri Lanka
Sunshine Coast University Hospital

Birtinya, Queensland, 4575, Australia
Teaching Hospital Kurunegala

Kurunegala, Sri Lanka
The First University Clinic of Tbilisi State Medical University

Tbilisi, 0141, Georgia
Universidade Federal de São Paulo

São Paulo, Brazil
University College Hospital Ibadan

Ibadan, Nigeria
University Kebangsaan Malaysia Medical Centre

Hulu Langat, Malaysia
University of Ilorin

Ilorin, Nigeria
Victoria Hospital

Kirkcaldy, KY2 5AH, United Kingdom
Zuyderland Medical Centre

Heerlen, 6419 PC, Netherlands

Conditions

Explore the condition pages connected to this study.

HYPERTENSION INTRACEREBRAL HAEMORRHAGE (ICH)