New drug combo shows promise in High-Risk breast cancer trial

NCT ID NCT05498896

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the drug ipatasertib to standard chemotherapy and immunotherapy (atezolizumab) can improve outcomes for women with high-risk triple-negative breast cancer before surgery. About 146 women with newly diagnosed, non-metastatic tumors that are at least 2 cm or have spread to lymph nodes are participating. The main goal is to see if the combination leads to no cancer remaining in the breast tissue after treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barts Health NHS Trust

    London, United Kingdom

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