Promising Triple-Drug cocktail targets tough leukemia mutation

NCT ID NCT06611839

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study tests a combination of three drugs—venetoclax, ivosidenib, and azacitidine—in adults with acute myeloid leukemia (AML) that has an IDH1 mutation. The goal is to see if this triple therapy can improve remission rates and survival. About 23 participants will receive the treatment, and researchers will monitor safety and effectiveness. This approach builds on earlier promising results in patients who couldn't tolerate standard chemotherapy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Blood Diseases Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.