Stem cells may predict who benefits from CF drug

This study tested the drug Trikafta in 42 people with cystic fibrosis who have rare gene changes not normally treated with this medicine. Participants took Trikafta for about four weeks, and researchers measured lung function and sweat chloride levels. They also took skin or blood samples to grow stem cells in the lab and see if those cells could predict who would respond to the drug. The goal was to find a faster way to match rare mutations with effective treatments.