Special oil may tame seizures in rare brain energy disorder
NCT ID NCT02014883
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested triheptanoin oil in 20 people with GLUT1 deficiency syndrome, a rare genetic condition that prevents glucose from properly fueling the brain. The goal was to see if this special oil could reduce the number of seizures and abnormal movement episodes. Participants took the oil and were monitored for safety and effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- triheptanoin oil
- What this could lead to
- If it works, this could provide a new treatment option to reduce seizures and abnormal movements in people with GLUT1 deficiency syndrome.
- What could go wrong
- This is a small, early-phase trial with only 20 participants, so results may not apply to all patients. There is also a risk of side effects like elevated propionylcarnitine levels, requiring dose adjustments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Brain and Spine Institute
Paris, 75013, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.