Triple-Drug combo aims to improve diabetes control and weight loss
NCT ID NCT07139405
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This study tests a new combination drug called TriGlytza-01 in overweight adults with type 2 diabetes whose blood sugar is not well controlled by metformin alone. The trial compares TriGlytza-01 to standard metformin over 16 weeks, measuring safety, blood sugar levels, and body weight. Participants are randomly assigned to one of three groups and take daily pills. The goal is to see if this triple-drug approach can offer better diabetes management.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TriGlytza-01 (a combination of metformin, celecoxib, and valsartan)
- What this could lead to
- If successful, this could offer a new combination treatment option for people with type 2 diabetes who need better blood sugar control and weight management.
- What could go wrong
- This is an early Phase 2a trial with only 48 participants, so results may not apply to everyone. The combination includes drugs with known side effects, and it may not prove more effective than existing treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Momentum Darlinghurst
Sydney, Australia
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Momentum Sunshine
Melbourne, Victoria, Australia
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UniSC Clinical Trials
Maroochydore, Queensland, Australia
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