Triple-targeting CAR-T cells aim to outsmart stubborn leukemia

NCT ID NCT05010564

First seen Nov 16, 2025 · Last updated Apr 30, 2026 · Updated 15 times

Summary

This study tests a new treatment for children and young adults (ages 1-25) with B-cell acute lymphoblastic leukemia (ALL) that has come back or not responded to standard therapy. The treatment uses the patient's own immune cells (T cells) that are modified in the lab to recognize and attack three different markers on leukemia cells (CD19, CD20, and CD22). The goal is to see if this triple-targeting approach is safe and can help control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.