New imaging tracks cancer drug in body

NCT ID NCT05638334

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study used PET scans to track where a new antibody drug (S095012) goes in the body and in tumors of people with advanced solid cancers. Only 3 participants were enrolled before the study was stopped early. The goal was to understand how the drug spreads and targets tumors, not to test if it works as a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

S095012 (a bispecific antibody targeting PD-L1 and 4-1BB) and a radioactive tracer (89Zr-S095012)

What this could lead to

If successful, this imaging approach could help doctors see which patients might benefit from S095012 treatment.

What could go wrong

This was a very small, early-phase study (only 3 participants) that was terminated early, so results are limited and may not apply broadly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UMC Gronningen Oncologie

    Groningen, 9713 AZ, Netherlands