Tailoring transplant prep: study aims to reduce toxicity in kids

NCT ID NCT06861257

First seen May 03, 2026 · Last updated May 15, 2026 · Updated 2 times

Summary

This study looks at how the chemotherapy drug treosulfan is processed in the bodies of 70 children (ages 0-18) receiving stem cell transplants for cancer or other blood disorders. Researchers will measure drug levels in the blood to see if adjusting the dose can reduce harmful side effects while still being effective. The goal is to find the safest and most effective dose for each child.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOU Città della Salute e della Scienza Di Torino, SC Oncoematologia Pediatrica e Centro Trapianti

    RECRUITING

    Torino, Torino, 10126, Italy

    Contact Phone: •••-•••-••••

  • Azienda Ospedaliera di Padova, Oncoematologia Pediatrica

    RECRUITING

    Padova, Padova, 35128, Italy

    Contact Phone: •••-•••-••••

  • Fondazione IRCCS Policlinico San Matteo, S.C. Ematologia 2 - Oncoematologia Pediatrica

    RECRUITING

    Pavia, Pavia, 27100, Italy

    Contact Email: •••••@•••••

  • Fondazione IRCCS San Gerardo dei Tintori - Clinica Pediatrica

    RECRUITING

    Monza, Monza-brianza, 20900, Italy

    Contact Phone: •••-•••-••••

  • IRCCS Istituto Giannina Gaslini, U.O.S.D. Centro Trapianto di Midollo Osseo

    RECRUITING

    Genova, Genova, 16147, Italy

    Contact Phone: •••-•••-••••

  • IRCCS Materno Infantile "Burlo Garofolo", SC Oncoematologia Pediatrica e SS Trapianto Di Midollo

    RECRUITING

    Trieste, Trieste, 34137, Italy

    Contact Phone: •••-•••-••••

  • Ospedale Donna Bambino Azienda Ospedaliera Universitaria Integrata, U.O.C. Oncoematologia Pediatrica

    RECRUITING

    Verona, VR, 37126, Italy

    Contact Phone: •••-•••-••••

  • Ospedale San Raffaele, U.O. Immunoematologia Pediatrica

    RECRUITING

    Milan, Milano, 20132, Italy

    Contact Phone: •••-•••-••••

  • Ospedali Civili, Presidio Ospedale Dei Bambini, Oncoematologia Pediatrica e TMO

    RECRUITING

    Brescia, Brescia, 25123, Italy

    Contact

  • Policlinico Sant'Orsola Malpighi, Clinica Pediatrica Oncologia Ed Ematologia Pediatrica "Lalla Seràgnoli"

    RECRUITING

    Bologna, bOLOGNA, 40138, Italy

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.